Senior Scientist, Mass Spectrometry, Mechanistic Biology and Profiling

Job Title: Senior Scientist, Mass Spectrometry, Mechanistic Biology and Profiling

Location: Cambridge, UK

Salary: Competitive + Excellent Employee Benefits!

Applications Deadline: August 04

Who we are:

Discovery Sciences is a multi-faceted department that drives early drug discovery across AstraZenecas global Research & Development portfolio. Mechanistic Biology and Profiling (part of Discovery Sciences), is a global, multidisciplinary department responsible for mechanism-of-action studies and compound profiling in support of the Oncology, Cardiovascular and Respiratory & Immunology portfolios.

What youll do:

This is an exciting opportunity for a dedicated scientist with expertise in mass spectrometry to play a pivotal role in covalent drug discovery projects within AstraZeneca R&D in Cambridge, UK.

Accountabilities:

In this laboratory-based position, you will be responsible for utilising and developing biochemical assays, primarily employing mass spectrometry endpoints, to profile covalent compounds, support chemical design, and advance drug discovery initiatives. Operating within a matrix organisation, you will collaboratively deliver high-quality data from covalent compound screening to facilitate project progression and present findings in both group and project team meetings. You will provide technical expertise across multiple drug projects simultaneously within a dynamic and fast-paced work environment.

Essential Skills/Experience:

PhD or equivalent industrial experience

Developing, validating and running mass spectrometry and biochemical assays and using recombinant protein

Experience measuring kinetics in biochemical reactions

Strong team player with good written and oral communication skills

Ability to tackle challenges creatively delivering innovative solutions

Desirable Skills/Experience:

Experience in pharma/biotech

Experience working with covalent modification of proteins

Pioneer a new future to meet global healthcare challenges

At AstraZeneca each and every one of us is bold in the belief that science should be at the centre of everything we do. Science can change the way we see the world and how we can impact the diseases that impact us. Science compels us to push the boundaries of what is possible. We trust in the potential of ideas and pursue them, alone and with others, until we have transformed the treatment of disease. AstraZeneca is a place where free thinking and creativity fuel our determination to make a difference to people's lives through science. To question. To challenge. To search. To deliver.

Our team thrives in a supportive atmosphere, equipped with state-of-the-art resources that empower professionals to celebrate both their triumphs and setbacks. With us, you will not only impact the future of medicine but also enjoy competitive compensation, benefits, and robust career development opportunities. Join us on this exciting journey to make a meaningful impact in the world.

So, whats next?

We welcome your application for this role no later than August 04.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Date Posted

14-Jul-2025

Closing Date

03-Aug-2025

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.