Senior Scientist in Translational Pathology, Oncology

Senior Scientist, Translational Pathology - Oncology: An Opportunity to Drive Impact in Cancer Research

This Senior Scientist position within AstraZeneca's Translational Pathology group presents a compelling opportunity for ambitious scientists to contribute significantly to the advancement of oncology therapeutics. Located at the forefront of translational science for a global oncology leader, this role offers the chance to impact a diverse portfolio of innovative programs, from early-stage clinical development to post-market support of approved targeted therapies.

Key Advantages for Potential Candidates:

• Impactful Work: You will directly influence clinical decision-making by executing routine biomarker analysis, interpreting data, and informing dose selection and drug combination strategies. Your work will be crucial in understanding cancer pathways and resistance mechanisms.
• Cutting-Edge Science & Technology: This lab-based role emphasizes the use of the "best available science and technology" within a Good Clinical Practice (GCP) environment, ensuring you are working with state-of-the-art methodologies.
• Career Development & Exposure: The position offers exposure to the pharmaceutical industry and the drug development process, providing invaluable career growth opportunities. Experience with novel therapeutics and an industry-leading portfolio is a significant advantage.
• Collaborative Environment: AstraZeneca fosters a culture of "courage, curiosity, and collaboration." You'll work within a matrix team and across global boundaries, gaining experience in cross-functional teamwork and communication.
• Focus on Patient Outcomes: The company's mission to "eliminate cancer as a cause of death" underscores a deep commitment to patient well-being, providing a strong sense of purpose and motivation.

Key Considerations for Your Career Path:

• Lab-Based Expertise: This role is fundamentally lab-based, requiring strong practical skills in areas such as manual or automated immunohistochemistry (brightfield or fluorescence) and microtomy. A willingness to excel in hands-on histopathology is essential.
• Regulatory Compliance: Working within a GCP environment means adherence to strict quality standards is paramount. Experience with GCP or ISO15189 is highly desirable, indicating a need for meticulous attention to detail and robust documentation practices.
• Biomarker Assay Development: A strong track record in the development and validation of biomarker assays is a core requirement. Candidates should be adept at translating scientific questions into robust analytical methods.
• Scientific Acumen & Problem-Solving: The role demands strong analytical skills, the ability to critically analyze data, and a proactive approach to troubleshooting. A scientific background with a focus on oncology or related fields will be highly beneficial.
• Desirable Skill Sets: While training will be provided, possessing experience in digital image analysis solutions, multiplexed immunohistochemistry, or in situ hybridization (ISH) assays will provide a distinct advantage and accelerate your integration into the team. Familiarity with sample tracking software is also a plus.
• Educational Background: A BSc or MSc in Biomedical Science or a related scientific discipline is the minimum requirement. Experience in an NHS or related clinical setting with HCPC registration is highly desirable, as is pharmaceutical industry experience.

For individuals passionate about making a tangible difference in the fight against cancer, this Senior Scientist position at AstraZeneca offers a dynamic and rewarding career path. It's an opportunity to leverage your scientific expertise within a globally recognized organization dedicated to pioneering new medicines and improving patient lives.