Research Fellow (Fixed term) (MED

A fantastic opportunity has arisen for a molecular biologist/protein biochemist, to join a dynamic team of scientists focused on the development and application of novel molecular diagnostics and therapeutics using the Nobel Prize winning technology of phage display. The post is based at the School of Veterinary Medicine and Science (SVMS), University of Nottingham, working in close collaboration with AFABILITY. AFABILITY promotes the awareness and availability of non-animal techniques and resources for the production of antibodies.  With recent highly successful milestones reached, significant support and collaborations formed, it is an ideal time to be joining the team. This project is funded by Danish charity Forsogsdyrenes Vaern and has been running on an annual renewable basis since 2018.

The main duty of this post will be to characterise two synthetic phage display libraries produced in a previous phase of this study. This will include the isolation of target-specific antibodies by phage panning, as well as antibody cloning, expression and purification and characterisation of binding in immunoassays. The post will also assist with training initiatives to disseminate knowledge for the efficient use of phage display technology to replace the use of animals in antibody production. The libraries are intended for use in a range of applications including molecular diagnostics and therapeutics. Using streamlined production and affinity maturation techniques that can be easily adopted, the libraries will be used to educate and assist the scientific community with technological advancements in the field of antibody production, moving away from the traditional hybridomas and polyclonal antibody production approaches. There will be opportunities to travel to international meetings to promote the technology in line with 3Rs core values.

This is a full time (36.25 hours), fixed term post until 31 March 2026. Job share arrangements may be considered. Requests for secondment from internal candidates may be considered on the basis that prior agreement has been sought from both your current line manager and the manager of your substantive post, if you are already undertaking a secondment role.

Please contact Professor Kevin Gough: kevin.gough@nottingham.ac.uk if you have further questions about this role. Please note that applications sent directly to this email address will not be accepted.

Closing Date: 22 Apr 2025 Category: Research and Teaching (R&T)