Senior Research Fellow in Structural Biology & Enzyme Design BJ)

Senior Research Fellow in Enzyme Discovery and Design: An Exciting Opportunity at the University of Southampton

The University of Southampton is embarking on a new and exciting chapter in enzyme discovery and design, and they are seeking a highly motivated Senior Research Fellow to be at the forefront of this initiative. This role presents a unique chance to integrate cutting-edge structural biology with advanced computational protein science, shaping ambitious research programs that bridge fundamental scientific inquiry with tangible translational applications.

If you are looking to make a significant impact in a vibrant, multidisciplinary environment that actively encourages collaboration, this position is an exceptional opportunity. You will contribute to the generation of new funding streams through collaborative grant applications and play a pivotal role in solidifying Southampton's international standing in structural biology and protein design.

Key Advantages for Candidates:

• Interdisciplinary Research: Immerse yourself in a dynamic research ecosystem where structural biology, computational approaches, and translational research converge. This environment fosters innovation and allows for the exploration of diverse scientific perspectives.
• Cutting-Edge Science: This role places you at the intersection of groundbreaking research, utilizing the latest advances in computational protein science to understand and redesign enzymes. You will be instrumental in shaping ambitious research programs.
• Translational Impact: Beyond fundamental discovery, this position offers the chance to translate research insights into intellectual property and practical applications, fostering strong collaborations with industrial and clinical partners.
• Leadership and Mentorship: As a Senior Research Fellow, you will provide scientific leadership, mentor junior researchers, and contribute to the strategic direction of research, fostering an inclusive and supportive team culture.
• Career Development: The University of Southampton is committed to supporting your research profile development, contribution to large collaborative programs, and the translation of your discoveries into broader societal benefits.
• Strong Funding Focus: There is a clear emphasis on developing and delivering externally funded research programs, with particular attention to UKRI BBSRC funding streams, offering excellent opportunities for securing research grants.
• Global Recognition: You will have the opportunity to represent Southampton’s research excellence on the international stage, presenting your work at national and global conferences and publishing in high-impact journals.
• Supportive Environment: Benefit from a dynamic and supportive research environment, equipped with cutting-edge facilities and a culture that champions collaboration. You'll also find generous holiday entitlement, closure days, and flexible working opportunities.

Key Considerations for Your Career Path:

• Research Focus: The core of this role involves leading research projects focused on understanding and redesigning enzymes. A strong foundation in both experimental structural biology (e.g., X-ray crystallography, cryo-EM) and computational protein science is essential.
• Grant Writing and Development: A significant aspect of this position involves contributing to and leading grant applications. Demonstrating experience in successful UKRI grant applications is crucial.
• Translational Experience: While not always essential, prior experience in enzyme redesign, immune-related proteins, computational protein engineering, and engagement with translational research or intellectual property development would be highly advantageous.
• Collaborative Spirit: This role thrives on collaboration. Excellent communication skills and a proven ability to work effectively within multidisciplinary teams are paramount.
• Mentorship and Supervision: The opportunity to mentor and supervise junior colleagues is a key component. Experience in fostering a supportive research culture will be highly valued.
• Strategic Contribution: You will be expected to contribute to grant strategy and the long-term sustainability of research programs, as well as actively engage with the University’s Precision Bioscience Theme.

This Senior Research Fellow position at the University of Southampton offers an exceptional platform for a motivated scientist to advance their career, contribute to pioneering research, and make a lasting impact in the field of enzyme discovery and design. If you are passionate about pushing the boundaries of scientific knowledge and translating discoveries into real-world applications, this opportunity warrants your serious consideration.