Medical Director, Kidney Disease, Early Clinical Development CVRM

This Medical Director position offers a compelling opportunity for physicians with expertise in kidney disease to make a significant impact at the forefront of early clinical and translational research. If you are driven by innovation and eager to shape the future of treatments for complex diseases, this role within AstraZeneca's Cardiovascular, Renal & Metabolism (CVRM) Translational Medicine & Clinical Development (TSCD) department presents a unique career advancement prospect.

Advantages for Potential Candidates:

• Pioneering Research: You will be instrumental in progressing a diverse pipeline of both small and large molecules targeting kidney disease, engaging in early clinical and translational research.
• Multidisciplinary Collaboration: The role thrives in a collaborative, multidisciplinary environment, allowing you to work alongside experts in CVRM and across various therapeutic areas, fostering a holistic approach to disease understanding and treatment.
• Strategic Influence: You will have the chance to contribute to framing development strategies and plans for compounds targeting not only kidney disease but also interconnected conditions like heart failure, type 2 diabetes, obesity, and metabolic dysfunction-associated steatohepatitis.
• End-to-End Clinical Trial Involvement: This position offers end-to-end responsibility for early phase I-II global clinical trials, from protocol design and conduct to data interpretation and reporting, ensuring scientific integrity and patient safety.
• Advancement of Novel Endpoints: A key aspect of the role involves advancing the development and validation of innovative nonclinical and surrogate endpoints, including imaging and biomarkers, which is crucial for accelerating drug development.
• Scientific Leadership and Visibility: You will represent TSCD internally and externally, engaging with key opinion leaders and contributing to scientific forums through presentations and publications, thereby enhancing your professional profile.
• Commitment to Diversity and Inclusion: The organization is dedicated to building an inclusive and equitable environment, welcoming applications from all qualified candidates and offering necessary accommodations throughout the recruitment process.

Key Considerations for Your Career Path:

• Focus on Early-Phase Development: This role is heavily focused on early phase clinical and translational research. Candidates should have a strong interest and aptitude for scientific exploration, hypothesis generation, and early-stage drug development.
• Interdisciplinary Expertise: While the core focus is kidney disease, understanding and integrating insights from cardiovascular and metabolic diseases is essential. A willingness to expand your knowledge base across these interconnected areas will be beneficial.
• Regulatory and Scientific Rigor: The position demands a strong command of clinical research principles, regulatory compliance, and a robust understanding of biomarkers, surrogate endpoints, and biostatistics. A track record of scientific contribution through publications will be highly valued.
• Stakeholder Engagement: Success in this role hinges on effective communication and collaboration with cross-functional teams, internal stakeholders, and external experts. Strong interpersonal skills and the ability to influence and engage diverse audiences are critical.
• Adaptability and Pace: The dynamic nature of drug discovery and development requires adaptability. You will be working in an environment that encourages bold thinking and aims to accelerate the delivery of life-changing medicines.
• Contribution to a Bold Vision: AstraZeneca emphasizes leadership at all levels. This role offers a significant opportunity to contribute to a bold vision for treating complex diseases, requiring physicians with both deep clinical and scientific expertise and strong leadership capabilities.

This Medical Director position is an excellent opportunity for a driven physician to contribute meaningfully to addressing critical unmet needs in kidney disease and related metabolic disorders. It offers a path for significant professional growth through impactful research, strategic influence, and collaborative innovation.