Research Associate in Chemical Biology (AP

Postdoctoral Research Associate Opportunity: Advancing Targeted Cancer Therapies

This compelling postdoctoral position, offered by the Lovell Lab in collaboration with AdvanCell, presents an exciting opportunity for a motivated researcher to contribute to the cutting edge of targeted radionuclide therapy (TRT). TRT is a rapidly evolving field with immense potential to revolutionize cancer treatment by delivering therapeutic radiation precisely to tumor cells, thereby minimizing damage to healthy tissues.

This 24-month contract, with a potential 12-month extension, offers a significant chance to deepen your expertise and make a tangible impact. A key component of this role involves travel to Brisbane, Australia, to foster collaboration with colleagues at AdvanCell, broadening your international research network and experience.

The Project: Pioneering Peptide-Based Radiomedicines

The core of this project is the identification of highly selective peptide binders. These binders will be developed using state-of-the-art peptide display technologies and will serve as crucial targeting vectors in the development of novel radiomedicines. The research integrates a sophisticated suite of methodologies, including:

• Phage or mRNA Display: Leveraging powerful techniques for the selection of high-affinity binders.
• Automated Solid-Phase Peptide Synthesis: Enabling efficient and precise synthesis of peptides.
• Direct-to-Biology Workflows: Streamlining the assessment of biological activity.
• Chemical Proteomics: Providing deep insights into molecular interactions.
• Structural Biology: Understanding the three-dimensional structures of key molecules.

Your Career Path: Key Advantages and Considerations

This role is ideally suited for a postdoctoral candidate with a strong foundation in chemistry, chemical biology, or a related discipline, who is eager to specialize in peptide drug discovery and cancer research. If you possess demonstrated expertise in display technologies (such as phage or mRNA display) and hands-on experience with solid-phase peptide synthesis, this position offers a platform for significant professional growth.

Advantages for Candidates:

• Specialized Skill Development: Immerse yourself in a multidisciplinary project that integrates advanced techniques, enhancing your technical skillset and marketability.
• Impactful Research: Contribute directly to the development of next-generation cancer therapies, a field with profound societal implications.
• International Collaboration: Gain valuable experience working with international partners, fostering cross-cultural understanding and expanding your global research network.
• Career Progression: The potential for an extension offers a stable and prolonged research experience. Furthermore, the University of Bath is committed to professional development, offering at least 10 days of pro rata professional development per year.
• Supportive Environment: The University of Bath champions diversity and inclusion, offering a welcoming environment for staff from all backgrounds. They also provide comprehensive benefits, including relocation assistance and visa reimbursement for international candidates.
• Potential for Advancement: A lower-grade offer (Grade 6 Research Assistant) may be considered for exceptional candidates, with a clear pathway to promotion upon PhD award, demonstrating a commitment to nurturing talent.

Key Considerations for Candidates:

• PhD Requirement: A PhD in Chemistry, Chemical Biology, or a closely related field is essential for the Grade 7 position.
• Technical Proficiency: Strong analytical skills, including proficiency in HPLC, LC-MS, or LC-MS/MS method development, are critical.
• Proactive & Independent Work Ethic: The role requires strong organizational, communication, and teamwork skills, coupled with the ability to work independently and proactively solve problems.
• Mentorship Opportunity: Willingness to supervise and train junior lab members is expected, providing valuable leadership experience.
• Relocation: Be prepared for travel and potential relocation to Brisbane, Australia, as part of the collaborative effort.

This Postdoctoral Research Associate position offers a unique blend of cutting-edge scientific research, international collaboration, and dedicated professional development, making it an exceptional opportunity for a driven scientist looking to make a significant mark in the field of cancer therapeutics.