Research Assistant/Associate in HTP Crystallography (Newcastle, GB)

Salary:

Research Assistant - £33,002 to £34,610 per annum

Reseach Associate - £35,608 to £37,694 per annum

Newcastle University is a great place to work, with excellent benefits. We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.

Closing Date: 23 January 2026

The Role

Applications are invited for a postdoctoral research position (PDRA) in single crystal X-ray diffraction, to work with Dr. Michael Hall and Prof. Michael Probert in Chemistry, at the School of Natural and Environmental Sciences (SNES), Newcastle University. This position is funded by Innovate UK as part of the Sustainable Medicines Manufacturing Innovation Programme (SMMIP), in collaboration with AstraZeneca and Indicatrix Crystallography. The role will be centred around the development of a high throughput single crystal X-ray diffraction platform, compatible with previously developed high throughput nanodroplet crystallisation methods developed at Newcastle (ENaCt, Chem 2020, 6(7), 1755-1765).

The full time post (1 FTE) will involve the development of methodology, instrumentation and workflows, to enable rapid high throughput single crystal X-ray diffraction analysis of small organic molecules, with a focus on pharmaceuticals. This will require extensive use of crystallisation methods and diffraction techniques to fully characterise molecular materials. The project will be performed in-house using the world-leading X-ray diffraction instrumentation available at Newcastle. The in-house facilities include 6 single crystal diffractometers with a range of X-radiation wavelengths available (Ag, Cu and Mo) alongside state-of-the-art liquid handling robots for high throughput crystallisation. This project will have dedicated use of a high specification modern single crystal diffractometer, to be installed in early 2026.

As part of a team, both at Newcastle and as part of the wider collaboration, you will be responsible for setting up and running experiments using bespoke crystallisation techniques and a unique suite of diffraction equipment, for which full training will be provided. Familiarity with single crystal X-ray diffraction techniques is a necessity with experience of instrumentation design a strong benefit.

You must hold, or be about to obtain, a PhD or equivalent in chemistry, physics, materials sciences, or a related field and a strong background in the analysis of crystalline materials. You should also have the ability to play a leading role within the research team. A track record of publishing research in high quality journals and experience supervising student research projects, commensurate with your experience level, is also desirable. You will also be encouraged to participate in the group’s vibrant outreach programme.

The appointment is available from January 2026 for an initial term of 12 months, with the potential for extension.

Please contact Dr Michael Hall [email protected] or Prof. Michael Probert [email protected] with informal inquiries about the post. Formal applications should be submitted through the University job applications portal.

As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level. Also include information about the Academic Service/Unit they will be working in covering strategic aims, values and culture.

Key Accountabilities

Perform original research to develop high throughput single crystal X-ray diffraction methodology and protocols, for small organic molecules Perform original research to develop instrumentation and equipment to facilitate throughput single crystal X-ray diffraction analysis Perform crystallisation experiments using both classical and modern methods Perform single crystal X-ray diffraction experiments, and will analyse the data obtained Effectively communicate and work within a large consortium team, including academic and industrial stake holders Prepare results for publication and presentation at conferences and seminars

The Person

Observational and practical skills consistent with the demands of contemporary scientific research Proven track record in data analysis Good communication skills and the ability to work within a team

Knowledge, Skills and Experience

A high standard of written and verbal English A high-level understanding of various crystallographic methods and techniques from crystallisation to extreme conditions diffraction Experience of collection of crystallographic data at both home laboratories and central facilities Experience of crystal structure solution and refinement from single crystal diffraction data Experience of preparation of crystallographic data for publication Experience with liquid robot handling techniques Skills in scientific instrument or experiment development Scripting programming language experience A record of publication commensurate with experience level Experience of the preparation and characterisation of crystalline samples Experience of non classical crystallisation protocols Attributes and Behaviour A desire to work with due attention to the safety of themselves and others. Self-motivation, a determination to succeed and a commitment to high standards The capacity to undertake original research and work independently A willingness to engage in research collaborations with co-workers across the project area A willingness to take on the day-to-day supervision of undergraduate project students as necessary

Qualifications

A PhD. in a related discipline (for appointment at Research Associate) or at least be on schedule to complete their PhD programme within 6 months of the start date (for appointment at Research Assistant)

Newcastle University is a global University where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution.

We are committed to being a fully inclusive university which actively recruits, supports and retains colleagues from all sectors of society. We value diversity as well as celebrate, support and thrive on the contributions of all of our employees and the communities they represent. We are proud to be an equal opportunities employer and encourage applications from individuals who can complement our existing teams, we believe that success is built on having teams whose backgrounds and experiences reflect the diversity of our university and student population.

At Newcastle University we hold a Gold Athena Swan award in recognition of our good employment practices for the advancement of gender equality. We also hold a Race Equality Charter Bronze award in recognition of our work towards tackling race inequality in higher education REC. We are a Disability Confident employer and will offer an interview to disabled applicants who meet the essential criteria for the role as part of the offer and interview scheme.

In addition, we are a member of the Euraxess initiative supporting researchers in Europe.

Requisition ID: 28984

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